When New Orleans celebrates its tricentennial in 2018, the Seignouret-Brulatour House at 520 Royal Street will enter a new chapter in its long and varied existence. The Historic New Orleans Collection purchased the property in 2006 and began planning for its transition to a museum facility with nearly 12,000 square feet of exhibition space. Since 2014, archaeological, restoration, and construction work have been ongoing. When the project is complete, the property will be divided into two parts, separated by the courtyard. The historic main building will house a major permanent exhibition on the history of the French Quarter, as well as exhibitions exploring the architecture and archaeology of the property. At the rear of the property will be a purpose-built museum exhibition facility comprising three state-of-the-art gallery spaces for changing exhibitions.

In June 2017, THNOC unveiled a scale model of the forthcoming facility accompanied by a history of the 200-year-old property, as well as information about the in-progress construction and planning for the facility.